PROVIDER RESOURCE / UROLOGY
2027 Prostate Biopsy CPT Updates
What Urology Providers Need to Document · Effective January 1, 2027
Published October 23, 2026 · Providers, practice administrators, and coding teams
Prostate biopsy coding changes again in 2027. Following the 2026 restructuring, the updated codes more clearly distinguish regional sampling, fusion-targeted sampling, and procedures that include both.
For providers, the priority is clear documentation of the approach, guidance technique, sampling performed, and distinct lesions targeted.
WHAT IS CHANGING?
| Code(s) | 2027 Change | Practical Impact |
|---|---|---|
| 55706 | Deleted | Separate transperineal stereotactic template-guided saturation biopsy code retired. |
| 55712 | Deleted | Transperineal fusion-targeted-only biopsy moves to revised 55711. |
| 55713 | Deleted | Separate in-bore regional-plus-targeted biopsy code retired. |
| 55707–55710 | Revised | Clarifies regional sampling and regional plus fusion-targeted sampling by approach. |
| 55711 | Revised | First fusion-targeted lesion without regional sampling; either approach. |
| +55716 | New | Each additional fusion-targeted lesion without regional sampling, with 55711. |
| 55714 / +55715 | Revised | In-bore CT/MRI-targeted biopsy: first lesion and each additional lesion. |
Descriptions are abbreviated educational summaries, not official CPT descriptors.
MATCH THE DOCUMENTATION TO THE PROCEDURE
| Procedure Documented | 2027 Code Pathway |
|---|---|
| Transrectal regional biopsy | 55707 |
| Transrectal regional and fusion-targeted sampling | 55708 |
| Transperineal regional biopsy | 55709 |
| Transperineal regional and fusion-targeted sampling | 55710 |
| Fusion-targeted-only biopsy, either approach | 55711 + 55716 for each additional targeted lesion |
| In-bore CT/MRI-targeted biopsy | 55714 + 55715 for each additional targeted lesion |
Key distinction: The new +55716 pathway applies to additional fusion-targeted lesions with 55711, when regional sampling is not performed. The revised +55715 pathway applies to additional in-bore CT/MRI-targeted lesions. Do not automatically carry 2026 add-on reporting into 2027.
BASIC DOCUMENTATION REQUIREMENTS
Your procedure note should clearly identify:
- Approach: Transrectal or transperineal.
- Guidance: Ultrasound, MRI-ultrasound fusion, or in-bore CT/MRI.
- Sampling: Regional, fusion-targeted only, or both.
- Targets: Number and location of distinct targeted lesions.
- Specimens: Cores obtained from each target and regional sampling, when performed.
Document lesion count separately from core count. Multiple cores taken from one lesion should not be described as multiple distinct targets.
PREPARE YOUR PRACTICE
Review biopsy templates, order sets, charge tickets, and coding workflows before January 1. Remove deleted codes and ensure the documentation supports the revised procedure categories. Imaging guidance is included in the listed image-guided biopsy descriptions; review CPT instructions before separately reporting associated imaging services.
Final code selection should follow the 2027 CPT descriptors and parenthetical instructions, applicable NCCI edits, and payer requirements. CPT changes do not independently establish coverage or payment.
NEED HELP UPDATING YOUR BIOPSY DOCUMENTATION?
MCRS provides focused provider education and documentation reviews to help practices connect the procedure performed with accurate reporting.
Contact MCRS to schedule a prostate biopsy coding and documentation education session.
Request Prostate Biopsy Education ↗Documentation Drives Medical Necessity.
SOURCES
- AAPC Codify: 2027 new, revised, and deleted CPT codes. Code changes verified against October 22, 2026 exports.
- AMA: CPT 2027 code set release.
- AUA: Review of 2026 prostate biopsy codes and 2027 preview.
- AMA CPT® 2027 Professional Edition: consult the complete prostate biopsy guidelines, descriptors, and reporting instructions.
CPT® is a registered trademark of the American Medical Association.